| アイテムタイプ |
default_学術雑誌論文 / Journal Article(1) |
| タイトル |
|
|
タイトル |
Encouraging Tactics with Genetically Modified Probiotics to Improve Immunity for the Prevention of Immune-Related Diseases including Cardio-Metabolic Disorders |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cardio-metabolic disorders |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
obesity |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
diabetes |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
MAFLD |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
NAFLD |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
PI3K |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
AKT |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
mTOR |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
probiotics |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
genetically modified probiotics |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
淺井 智子
Yoshikawa Sayuri
池田 祐香
Taniguchi Kurumi
Sawamura Haruka
辻 愛
松田 覚
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The PI3K/AKT/mTOR signaling pathway may play crucial roles in the pathogenesis of obesity and diabetes mellitus, as well as metabolic syndromes, which could also be risk factors for cardio-metabolic disorders. Consistently, it has been shown that beneficial effects may be convoyed by the modulation of the PI3K/AKT/mTOR pathway against the development of these diseases. Importantly, the PI3K/AKT/mTOR signaling pathway can be modulated by probiotics. Probiotics have a variety of beneficial properties, with the potential of treating specific diseases such as immune-related diseases, which are valuable to human health. In addition, an increasing body of work in the literature emphasized the contribution of genetically modified probiotics. There now seems to be a turning point in the research of probiotics. A better understanding of the interactions between microbiota, lifestyle, and host factors such as genetics and/or epigenetics might lead to a novel therapeutic approach with probiotics for these diseases. This study might provide a theoretical reference for the development of genetically modified probiotics in health products and/or in functional foods for the treatment of cardio-metabolic disorders. |
|
言語 |
en |
| 書誌情報 |
en : Biomolecules
巻 13,
号 1,
p. 10,
発行日 2023
|
| 出版者 |
|
|
出版者 |
MDPI AG |
|
言語 |
en |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2218-273X |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.3390/biom13010010 |
| 権利 |
|
|
権利情報 |
© by the authors |
|
言語 |
en |
https://doi.org/10.3390/biom13010010
