| アイテムタイプ |
default_学術雑誌論文 / Journal Article(1) |
| タイトル |
|
|
タイトル |
A New Concept of Associations between Gut Microbiota, Immunity and Central Nervous System for the Innovative Treatment of Neurodegenerative Disorders |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
gut microbiota |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
engram |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
neurodegenerative disorders |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Alzheimer’s disease |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Parkinson’s disease |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
amyotrophic lateral sclerosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
schizophrenia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
inflammation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
reactive oxygen species |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
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|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
Yoshikawa Sayuri
Taniguchi Kurumi
Sawamura Haruka
池田 祐香
辻 愛
松田 覚
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Nerve cell death accounts for various neurodegenerative disorders, in which altered immunity to the integrated central nervous system (CNS) might have destructive consequences. This undesirable immune response often affects the progressive neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, schizophrenia and/or amyotrophic lateral sclerosis (ALS). It has been shown that commensal gut microbiota could influence the brain and/or several machineries of immune function. In other words, neurodegenerative disorders may be connected to the gut–brain–immune correlational system. The engrams in the brain could retain the information of a certain inflammation in the body which might be involved in the pathogenesis of neurodegenerative disorders. Tactics involving the use of probiotics and/or fecal microbiota transplantation (FMT) are now evolving as the most promising and/or valuable for the modification of the gut–brain–immune axis. More deliberation of this concept and the roles of gut microbiota would lead to the development of stupendous treatments for the prevention of, and/or therapeutics for, various intractable diseases including several neurodegenerative disorders. |
|
言語 |
en |
| 書誌情報 |
en : Metabolites
巻 12,
号 11,
p. 1052,
発行日 2022
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| 出版者 |
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|
出版者 |
MDPI AG |
|
言語 |
en |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
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収録物識別子 |
2218-1989 |
| DOI |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
10.3390/metabo12111052 |
| 権利 |
|
|
権利情報 |
© MDPI |
|
言語 |
en |
https://doi.org/10.3390/metabo12111052
